Objective: To determine the association of physical activity with mitochondrial DNA copy number (mtDNA-CN) in eveningness chronotype.
Methodology: In this cross-sectional analytical study, 80 eveningness chronotypes were recruited by distributing the morningness-eveningness questionnaire (MEQ). Physical activity levels of participants were assessed by using International Physical Activity Questionnaire (IPAQ), and 2 groups were made. Group A included active (n=40) and Group B included inactive participants (n=40). Mitochondrial DNA copy number of all the participants was determined by quantitative polymerase chain reaction (PCR). Data were analyzed using SPSS 27.
Results: A total of 80 participants (Male=30, Female=50) with mean age of 24.27±6.91 years (range 18-45 years) were included in the study. Mean mitochondrial DNA copy number (log-transformed) was significantly higher in active participants as compared to inactive ones (p
Key words: Mitochondria, mitochondrial DNA, oxidative stress, chronotype.
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