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Oxidative stress: the dark side of soybean-oil-based emulsions used in parenteral nutrition

Livan Delgado Roche.


Soybean-oil based lipid emulsion have been used for parenteral nutrition since 1980’s decade. These kind of pharmaceutical formulations represent an important energy source to critically ill patients. But it has been demonstrated that soybean-based-lipid emulsions induce a hyperlipidemic state and oxidative stress, which represent the major complications of these energy sources. The aim of the present work was to review the state of the art on lipid emulsions and its relationship with oxidative stress, and associated diseases.

Key words: Hyperlipidemia; Lipid emulsions; Parenteral nutrition; Oxidative stress

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