Study on drug prescribing pattern in hypertensive patients in a tertiary care teaching hospital at Dehradun, UttarakhandMirza Atif Beg, Shaktibala Dutta, Amit Varma, Ravi Kant, Shalu Bawa, Mohammad Anjoom, Saubhagya Sindhu, Santosh Kumar.
Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilisation studies are an important tool to promote rational prescribing.
Aims & Objective: To study on drug prescribing pattern in hypertensive patients.
Materials and Methods: A drug utilisation study was conducted in hypertensive patients by the department of pharmacology in medicine OPD at SGRRIM & HS, Dehradun for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators.
Results: 645 prescriptions were analysed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensives, 243 (13.30%) antidiabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin receptor blockers (ARBs), 117 (16.79%) angiotensin converting enzyme (ACE) inhibitors, 95 (13.63%) Beta blockers, 83 (11.91%) Calcium channel blockers 168 (24.10%) Fixed dose combinations (FDCs) of antihypertensives were included. 2.83 drugs were prescribed per prescription. 225 (32.28%) antihypertensives were prescribed from essential medicine list.
Conclusion: Most commonly prescribed drugs were ARBs and ACE inhibitors. Rational prescribing requires consideration to dose and duration and interaction with other medications.
Drug utilization, rational prescribing, fixed dose combinations, therapeutic audit.