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Structure-activity Relationships of Antioxidant Activity in vitro about Flavonoids Isolated from Pyrethrum Tatsienense

Chao-Zhan Lin, Chen-Chen Zhu, Min Hu, Ai-Zhi Wu, Bairu Zeren-dawa, Kangsa Suolang-qimei.




Abstract

Pyrethrum tatsienense (Bur. et Franch.) Ling is mainly used to treat hepatitis, headaches, head injuries, ulcers, and wounds in Tibet. The aim of this study was to investigate the antioxidant activity of eleven flavonoids mainly revealing luteolin as mother nucleus isolated from Pyrethrum tatsienense, and further elaborate the structure-activity relationships of antioxidant activity about these flavonoids. The above study would provide some theoretical basis for the obvious therapeutic effects of this Chinese medicine.

Key words: Pyrethrum tatsienense; flavonoids; antioxidant activity; structure-activity relationship






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