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White matter abnormalities and Virchow Robin spaces in patients with psychotic disorders

Osman Özdemir, Pınar Güzel Ozdemir, Vedat Cilingir, Mehmet Deniz Bulut, Damla Kement Timucin.

Abstract
In this study, we aimed to present white matter abnormalities and Virchow Robin spaces in patients with psychotic disorders and to discuss possible underlying mechanisms. The patient sample comprised 24 patients with psychotic disorders who had white matter abnormalities on MRI. Magnetic resonance imaging (MRI) appeared periventricular white matter changes in twelve patients (%50,0), frontal lesions in six patients (%25,0), parietal lesions in six patients (%25,0), temporal lesions in one patients (%4,2), infratentorial lesions in two patients (%8,3), and Virchow Robin spaces in eight patients (%33,3) This study suggested that there is a relationship between white matter abnormalities and psychotic disorders.

Key words: White matter abnormalities, Virchow Robin space, psychotic disorder,



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