Aim: The aim of this study was to investigate the factors that cause urinary tract infections (UTI) and antibiotic susceptibility profiles with epidemiological and clinical features among children hospitalized with the diagnosis of UTI.
Materials and Methods: This study was retrospective and evaluated the clinical and laboratory features of 216 patients aged 0-15 years old evaluated, who were hospitalized with a diagnosis of UTI in a single center.
Results: The mean age of patients with confirmed UTI was 3.75±3.73, with a male-to-female ratio of 2:1. Fever was the most common symptom observed. In patients with confirmed UTI, urine nitrite positivity and high leukocyte positivity were significantly elevated (p=0.0001). Urine culture yielded positive results in 43% of the patients, with Escherichia coli (E. coli) being the most frequently detected pathogen. High rates of resistance were observed for the antibiotics ampicillin, cefuroxime, ceftriaxone, and trimethoprim-sulfamethoxazole (TMP-SMX), while resistance to aminoglycosides, nitrofurantoin, and carbapenems was less frequently encountered.
Conclusion: Urine nitrite and high leukocyte positivity may be suggestive of a diagnosis of UTI in patients without positive urine culture results.
Key words: Urinary tract infection, children, antibiotics, epidemiology, pediatric healthcare, antibiotic resistance
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