Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Article

In vitro modulation of pancreatic insulin secretion, extrapancreatic insulin action and peptide glycation by Curcuma longa aqueous extracts

Violet Kasabri, Peter R. Flatt, Yasser H. A. Abdel-Wahab.

Objective: Medicinal, edible and aromatic plants have been used as folk remedies in traditional treatments worldwide. This study investigates the antidiabetic efficacy and action mode of Curcuma longa Linn. (Zingiberaceae).
Methods: Effects of aqueous extracts (AEs) of C.longa on insulin secretion and action were studied using the insulin-secreting BRIN-BD11 and the adipocyte-like 3T3-L1 cell lines, respectively. In vitro models were employed to evaluate effects on starch digestion using alpha-amylase/amyloglucosidase and protein glycation.
Results: C.longa AEs stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (P

Key words: Curcuma longa Linn. (Zingiberaceae), insulin action, insulin secretion, peptide glycation, starch digestion

Full-text options

Full-text Article

Progress in Orthopedic Science


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.