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A study of 25 cases of cerebral venous thrombosis

Zalak Darji, Leena Dabhi.




Abstract

Background: Cerebral venous sinus thrombosis is a rare but dangerous condition, occurring with an incidence of 3-4 cases/ million/ year. It has a higher frequency among patients younger than 40 years of age. Cerebral venous thrombosis occurs 3 times as frequently in women. The symptoms and signs associated with cerebral venous thrombosis (CVT) are relatively nonspecific.

Aims & Objective: To study the demographic profile, identify various etiologies different mode of onset and presentations, identify common sites of occlusion and outcome of the patients with CVST.

Materials and Methods: Total 25 patients admitted in medical wards with MR venography suggestive of CVST were enrolled. Detailed medical history with general and systemic examination done. Routine and specific investigations carried out. Patients treated with anticoagulation therapy. At time of discharge recovery is graded in form of Modified Rankin Score.

Results: Higher incidence in young female of 21 – 30 age group. Male to female Ratio was 1:3.167. Pregnency and puerperium accounts for 36%of total cases. Headache was presenting symptom in all patients. CSF was abnormal in 17 patients. Superior sagittal sinus alone or in combination affected in 72% of cases.52% of patients had complete recovery. Death occurred in 20% of cases.

Conclusion: Sinus thrombosis remains a diagnostic challenge and a potentially disabling or lethal disease, but improved diagnosis by recent advances and treatment now result in an excellent outcome for most patients.

Key words: Cerebral Venous Sinus Thrombosis; Pregnency and Puerperium; Superior Sagittal Sinus






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