use of non-conventional uterine immunomodulators such as colostrum and non pathogenic E.Coli show excellent results in reducing the bacterial population and also improving the conception rate.The cows subjected to normal saline treatment (Control Group ) projected a first insemination conception rate of 42.86%, out of seven cows. Seven cows intrauterine treated with colostrum (Group I) recorded a pregnancy rate of 57.14%. The nonpathogenic E.coli induced group (Group II), three cows became pregnant (42.86%) out of seven inseminations. Colostrum and non-pathogenic E.coli have shown excellent result in reducing the bacterial population significantly.
Key words: immunomodulation, colostrum and non pathogenic E.coli
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