Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

RMJ. 2013; 38(1): 64-65


The use of pentaglobulin in neonatal immune hemolytic anaemia

Hashem Ezzat Aqrabawi.




Abstract

Objective: To evaluate the efficacy of pentaglobulin in reducing the rate of exchange transfusion among neonates with immune hemolytic anaemia.
Method: An observational prospective study that was conducted over two year's period starting from January 2010 to January 2012. Pentaglobulin was given in a dose of 1 gm/Kg/day for all newborns with the following criteria: immune hemolytic anaemia; high or rising level of bilirubin approaching exchange transfusion. Phototherapy was used in conjunction with pentaglobulin.
Results: The total number of newborns who received pentaglobulin over that period of time was 85 infants. None of them required exchange transfusion. Ten newborns required top up transfusion. The duration of phototherapy application ranged from 48 to 72 hours.
Conclusion: The study shows that early use of pentaglobulin in immune hemolytic anaemia reduces the risk of exchange transfusion and the duration of phototherapy application. Further randomized controlled trials are needed to verify the results of our observations.

Key words: Exchange transfusion, pentaglobulin, phototherapy






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.