Objective: To evaluate oral Ivermectin as a
therapeutic agent to ordinary scabies.
Methodology: Random sample of 50 cases of
ordinary scabies was treated with two oral doses
of Ivermectin, 200 μg/kg one week apart. The
effect of the drug was monitored clinically, by
complete blood count, and confirmed
parasitologically at the time of clinical
presentation and at week 4 of starting treatment.
ELISA and Immunobloting using Sarcoptes
scabiei crude mite extract were applied
to determine the levels of specific IgG and IgE in
patients' sera in comparison with 50 controls.
Results: The reported cure rate was 100%.
However, 8% cases continued to have persistent
itching, accompanying eosionophilia and high IgE
levels.
Conclusion: Ivermectin proved to be effective and
promising drug for treatment of ordinary scabies.
(Rawal Med J 2013; 38:127-130).
Key words: Scabies, Ivermectin, ELISA,
Immunoblotting.
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