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A study to evaluate the relation between the age at menarche and bone mineral density in pre- and post-menopausal women

Swati Vikas Gavit, Laxmi Sachin Patel, Bhakti Mandar Dhamangaonkar.


Background: Bone mass loss is very common but ignored problem of elderly population. Many reproductive and menstrual factors such as parity, breastfeeding, age at first pregnancy, age at menarche, use of combined oral contraceptives, and age at menopause affect bone mineral density (BMD). Major hormonal changes occur at menarche; also, the age at which menarche attained is not same for all females.

Aims and Objectives: The present study aimed to evaluate the correlation between the age at menarche and BMD in premenopausal and postmenopausal women.

Materials and Methods: The study was conducted at tertiary care medical college and general hospital and at private hospitals of the metropolitan city on 73 normal healthy women in the age group of 20–75 years. Their age, sex, body mass index, age at menarche, and BMD values were recorded. BMD was measured by DXL Calscan (Demetech AB).

Results: The readings were analyzed by Pearson Chi-square test. In the present study, we did not find any correlation between age at menarche and BMD.

Conclusion: Many reproductive parameters including age at menarche are an important determinant of BMD; therefore, it is suggested that educational strategies are needed to increase awareness of factors that contribute to maintaining bone health among females.

Key words: Age at MENARCHE; Bone mineral density; Postmenopausal; Premenopausal

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