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Original Article

J App Pharm Sci. 2019; 9(4): 126-132


A prospective observational study on cardiovascular risk assessment in type-2 diabetes mellitus patients

Laxmidhar Maharana, Sateesh Kumar Reddy K., Snigdha Pattnaik, Siraz Ahmed, Divya Teja V., Bhargavi K., Syed Shabbir Hussain, Manoj Kumar Sethi.




Abstract
Cited by 2 Articles

Objective: Atherosclerotic cardiovascular diseases were the major culprit in diabetic patients with high mortality rate in non-communicable disease worldwide. Present study was conducted to assess cardiovascular risk among type-2 diabetic patients without the history of cardiovascular disease.
Methods: The present study was conducted on type-2 diabetes patients without history of cardiovascular disease and no. of samples was 118[65 male and 53 female] aged between 36-74 years in a teaching hospital of southern part of India. The individual patient risk factors were determined. Framingham cardiovascular risk prediction model was used to calculate the 10 year risk for CVD. The relationship between Framingham Cardiovascular risk score and individual risk factors were determined using chi-square test.
Key findings: FRS-CVD (Framingham risk score for cardiovascular disease) risk assessment model shows 11.01% were at high risk, 33.05% were at intermediate risk and 55.93% were at low risk for developing CVD in the next 10 years. Visceral adiposity index, waist circumference, waist height ratio, smoking, SBP, DBP contributed significantly to high degree of cardiovascular risk.
Conclusion: The results of our study concluded that in this population of patient with type-2 diabetes mellitus estimated cardiovascular risk in relationship with the central obesity but not with glycemic control parameters. The use of CVD assessment tools like framingham risk score, visceral adiposity index and ankle braquial index can prevent the diabetic patient from cardiovascular disease.

Key words: cardiovascular disease, type-2 diabetes mellitus, Framingham risk score, Ankle braquial index, visceral adiposity index






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