Background: Intramuscular myxomas are rare tumors of mesenchymal origin and are usually presented in skeletal or cardiac muscles. They are of gelatinous texture and tend to reach large dimensions. They usually present as a painless mass which grows significantly with time, but rarely causing symptoms as pain or pressure to nearby structures. Intramuscular myxomas are usually diagnosed with ultrasound, computed tomography scan or magnetic resonance imaging scan, but the definite diagnosis is acquired by the histology report of the excised mass.
Case Presentation: We report a rare case of a large (4 x 4 cm) symptomatic myxoma of the left thigh in a 49-year-old female.
Conclusion: Intramuscular myxomas are rare tumors of mesenchymal origin, which can reach large dimensions. Excision is advised, even in smaller-sized masses, in order to have a definite diagnosis.
Key words: Case report, myxoma, desmoid tumor
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