Home|Journals|Articles by Year|Audio Abstracts RSS - TOC
 

Review Article



Comprehensive reviews on phenolic compounds from Phaeophyceae as potential therapeutic agent

V. Maheswari, P. Azhagu Saravana Babu.




Abstract

Seaweeds are an excellent source of natural bioactive compounds. The exploration of novel natural compounds from marine resources has gained interest lately which possesses greater pharmaceutical and nutritional values. Seaweed phenolic compounds, particularly phlorotannin, have been discovered to have a variety of biological implications. Phlorotannin is a polyphenol that is found majorly in brown seaweed and is made up of polymeric units of phloroglucinol. The structural configuration and degree of polymerization were shown to influence biological activity. Several in vitro studies demonstrated that the phlorotannin derivatives had substantial bioactivity and were moderately appraised in vivo. Antioxidant, anticancer, anti-inflammatory, anti-allergic, anti-diabetic, and anti-microbial effects have been discovered in phlorotannin compounds. Recently, they have been evaluated for exhibiting anti-viral capacity against various harmful viruses. The findings suggested that phlorotannin could be an effective anti-viral molecule that requires intense research. This review focuses on the advanced techniques and research based on the experiments on phlorotannin for their extraction and purification. The phlorotannin as a potential drug molecule has been described from extraction to application. With the advent of technology, it is now possible to isolate the target molecule efficiently in less time. To make phlorotannin a novel nutraceutical and pharmaceutical molecule with wide industrial uses, preclinical and clinical research is required to assess its efficacy, toxicity, bioavailability, and drug delivery mechanism.

Key words: Bioactivity, Drug molecule, Phaeophyceae, Phenolic compounds, Phlorotannin.






Full-text options


Share this Article



Online Article Submission
• ejmanager.com
• ojshosting.net




eJManager.com
Review(er)s Central
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.