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Research Article



Evaluation of MRI findings in patients with the first episode of seizures

MAHYAR MOHAMMADIFARD, ELHAM RAHIMIAN, ELHAM PISHNAMAZ, MAJID.R TAHSINI.




Abstract

Introduction: Finding the cause of seizures has always been one of the most important problems for physicians. Magnetic resonance imaging (MRI) imaging in patients with seizures is one of the most important imaging modalities in detecting the structural abnormalities in seizures. Therefore, the aim of this study was to evaluate the prevalence of abnormal findings in the MRI of patients with the first episode of seizure.
Materials and Methods: This descriptive cross-sectional study was performed on patients referred to two imaging centers with (3T trio Siemens and 1.5T Avanto) with the first episode of seizure. Initially, the report of clinical diagnostic measures and demographic characteristics as well as clinical history, neurological examination and then MRI report were collected in a special checklist. MRI was performed by two MRI machines (3T trio Siemens and 1.5T Avanto) with dedicated protocol of seizure. After data collection, analyzing the data by SPSS software version 19 was performed and final results were extracted.
Results: A total of 1576 patients with a mean age of 30.1 years were evaluated, of whom 776 (49.2%) were female. The type of seizure was generalized in 1478 patients (93.8%) and focal in other patients. Abnormal findings were detected in MRI images of 619 patients (39.3%), the most common of which were temporal sclerosis in 193 patients (12.2%) and scar and gliosis in 117 patients (7.4%). The most lesions were found in the temporal lobe of 265 patients (45.5%). The frequency of normal and abnormal MRIs were significantly different between the sexes (P = 0.011), between different age groups (P

Key words: Magnetic resonance imaging seizures, MRI.






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