|JCDR. 2021; 12(3): 2747-2756
COMPARISONOFLEFTVENTRICULARHYPERTROPHYAMONGNORMOTENSIVETYPE 2 DIABETES MELLITUSPATIENTS WITHTHAT OF AGE-ANDGENDER-MATCHEDNON-DIABETICPATIENTS.Ashfaq Ahmad, Fazal Shafiq,Syed Arshad Ullah,Afiat Shaheen,Syed Noor Ullah Shah Fazal Saboor,Noor Alam,Muhammad Ismail,Seraj Uddi,Nget Sreynith,Sher Azim..
Background: Adverse cardiac outcomes like morbidity and mortality are eventually associated with Type 1 or Type 2 DM. The cardiovascular risk may eventually be increased with increased LVM. LVM is a life-threatening prognostic sign because of developing ventricular arrhythmia, myocardial ischemia, CHD, and HF.
Aim: This cross-sectional study aimed to evaluate the prevalence and risk factors for the development of LVH in age-and gender-matched normotensive population with T2DM and comparison of LVH among diabetic and non-diabetic normotensive patients
Methods: A total of 300 populations were included in this study.150 who were non-hypertensive with known T2DM and a similar number of healthy age- and gender-matched, non-diabetic, and normotensive controls. All the subjects of known diagnosed with T2DM with on oral or injectable anti-diabetic medication or patients with fulfilling the American Diabetic Association criteria for DM without any medical therapy. The baseline data were collected and LVM and LVMi were calculated by using echocardiographic parameters and BSA.
Results: LVM and LVMI were significantly higher in T2DM patients compared with the age-and gender-matched control population (231.7±30.38 vs 190.8±25.18 g/m2 with all P
Key words: Left ventricular hypertrophy, Diabetes mellitus, left ventricular mass, left ventricular mass index,