Abstract

Myocardial ischemia is defined as a diseased condition which is caused by reduced oxygen supply in a blood flow of coronary artery due to atherosclerosis and occlusion of an artery bya thrombus. Myocardial ischemia is caused by blockage of coronary blood flow by coronary plaques, blood clot and shrinking of macro vascular coronary arteries in the estrogen hormone state. The impaired fibroblast regulation is involved in the immuno pathogenesis of a wide variety of cardiovascular diseases and therefore is an important therapeutic target.

Key words: Myocardial ischemia, Atherosclerosis, Arteries.