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Research Article

JCDR. 2021; 12(4): 964-970


Clinico-Demographic Profile and Lab Findings Among Dengue Patients Diagnosed at a Tertiary Care Facility at Bihar

Dr. Rakesh Kumar, Dr. Ganesh Prasad Singh, Dr. Kunal, Dr. Sagar Rajak, Dr. Anil Kumar Gupta.


Abstract

Aim: The aim of the study was to determine the clinical spectrum of dengue at a tertiary care hospital in Bihar region. Methods: A prospective study was conducted in the Department of General Medicine, Vardhman institute of medical sciences, Pawapuri, Nalanda, and Bihar, India .Total 90 patients
with complaints of fever and clinical features of dengue with positive NS1 antigen test or dengue antibody serology IgM or IgG or both were included in the study. Results: Most of the cases (45.56%) were seen in the 20-30 year age group followed by 40-50 years 22.22%, 30-40 years 14.44%. Majority of the patients were males 58 (64.44%) compared to females, 32(35.56%) and the male to female ratio was1.81:1. Fever was the most common presentation and was seen in 45 cases (50%) cases and followed by Fever and Myalgia 13.33%, Myalgia 11.11%, Petechiae 8.89%, Fever and Skin rashes, Nausea and vomiting and Fever and Itching. Present study showed hemoglobin range of 6.5 gm% to 16.5 gm%. 41 (45.56%)
cases showed Hb of 9-12 gm %, followed by 27(30%) cases showed Hb of 12-15 gm %, 7 (7.77%) had Hb of below 9 gm % and 15 (16.67%) had Hb of above 15 gm%. In the present study, 50(55.56 %) cases showed hematocrit of 25-35% and 25(27.77 %) showed hematocrit of 35-45%. Raised hematocrit (>45%) was noted in 15(16.67%) of patients at presentation. The total leukocyte count ranged from 1500 cells/cumm to >11000 cells/cumm. Leucopenia withless than 4000 cells/cumm was present in 17(18.89%) cases , count of 4000- 11000 cells/cu mm seen in 58(64.44%) cases and >11000/ cumm was seen in 15 cases(16.67%). Conclusion: Hemoconcentration, leucopenia, thrombocytopenia, and raised liver enzymes
SGOT and SGPT along with reactive/ plasmacytoid lymphocytes on peripheral smear gives enough clues to test for dengue serology so that dengue cases can be diagnosed in their initial stages.

Key words: Dengue, Hb, platelets






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