Home|Journals|Articles by Year|Audio Abstracts

Review Article

Myocarditis as a prevalent cardiovascular complication in Omicron patients

Darren Junior, Cokorda Agung Wahyu Purnamasidhi, Giovanca Verentzia Purnama, Richard Christian Suteja, I Komang Hotra Adiputra, Jerry Jerry, I Gede Purna Weisnawa, Putu Kintan Wulandari, Dewa Ayu Fony Prema Shanti, I Gusti Ngurah Ariestha Satya Diksha.


Ever since the first outbreak of SARS-CoV-2 in late December 2019 in China, it has undergone a significant number of mutations and manifested itself in different variants worldwide. One of the latest variants, namely the Omicron variant has proved to possess novel characteristics including a shift in its entry pathway. Studies have shown that the Omicron variant has adapted to enter host tissue more efficiently through endosomal pathway rather than cell fusion as shown in its predecessors. As far as coronaviruses are concerned, there are several modes of entry for endosomal pathway including the caveolae formation pathway which is mediated by proteins called caveolins. One of the caveolins in particular is found abundantly in cardiomyocytes, thus posing as a higher risk for the Omicron variant to directly invade the heart tissue.

Key words: Entry Route, Myocarditis, Omicron, COVID-19, Pathophysiology

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.