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Original Research

BMB. 2022; 7(1): 56-62


Quantitative Volumetric CT Analysis of COVID-19 Pneumonia and Correlation with Neutrophil-Lymphocyte Ratio

Bora Kalaycıoğlu, Bahattin Özkul, Onural Öztürk.




Abstract

Abstract
Objective
Although scientific community has various knowledge about coronavirus pandemic, further studies are needed about its nature. The aim of our study is to explore the relationship between the imaging and laboratory findings of COVID-19. 
Material and Methods
Our study is a retrospective single-center study of patients with COVID-19. Patients with chest computerized tomography and with positive reverse-transcription polymerase chain reaction test results were examined. Total lung volume and lesion volume was calculated semi-automatically by Osirix software. Interclass correlation coefficient was used for testing consistency between the observers. Patients were divided into three groups as mild, moderate, and severe by involved lung volume. The relationship between laboratory findings and radiological severity investigated with area under curve in receiver operating characteristic plot.
Results
One hundred and six patients were included (female: 44, male: 62) in this study and median age was 55 years. The most common radiologic features were peripheral, multifocal, ground glass opacities with subpleural and basal distribution. Positive and moderate correlation was found between the percentage of involvement and the neutrophil to lymphocyte ratio (N/L) (rho= 0.635, p

Key words: COVID-19, Computed tomography, Neutrophil to lymphocyte ratio. Bilgisayarlı tomografi, COVID-19, Nötrofil/lenfosit oranı






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