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Evaluation of bacteriological profile of pyogenic infections and their susceptibility profiles at a tertiary care hospital

Wajid M, Shazia Naaz, Syeda Saba Hashmiya.




Abstract
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Introduction: Pyogenic infections are an important cause of sepsis and their prompt recognition and therapy are required to prevent inadvertent complications.
Methodology: A retrospective analysis of 302 culture-positive pus and wound samples received in the department of Microbiology between January 2020 to December 2020 was conducted. Data about the pathogen isolated and its antimicrobial susceptibility was subjected to analysis using WHONET software. Identification and susceptibility testing was done using the standard microbiological procedures.
Results: Among the samples male to female ratio [M: F-2.02:1] was skewed in favour of males with the majority of patients being between the age group of 40 - 60 yrs. Predominantly Gram-negative bacilli were isolated in 65.2% [197/302]. Among the Gram-negative bacilli, Escherichia coli was the most common pathogen isolated [35.5%, 70/197]. Gram-positive organisms were isolated in 34.7% [105/302] of cases and Staphylococcus aureus was the predominant organism isolated in 56.1%, [59/105].
Conclusion: This study accentuates the need for probing into the pattern of increasing trends of Multidrug-resistant [MDR] bacteria and frames an effective hospital-based policy for providing fruitful treatment in such cases.

Key words: Multidrug-resistant, E.coli, S.aureus, wound infections






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