Home|Journals|Articles by Year|Audio Abstracts RSS - TOC

Original Article

pnr. 2014; 5(1): 25-28

Inefficiency of ethanolic extract of Glycyrrhiza glabra and Ziziphus mauritiana roots on androgenic alopecia

Sukirti Upadhyay, AK Ghosh, Vijender Singh.


Aim: To study the air growth promoting effect of roots of G. glabra and Z. mauritiana in androgen (testosterone) induced male pattern baldness (androgenic alopecia). Materials and Methods: Animals were divided into four groups and they were attempted to made alopecic by treatment with testosterone for 3 weeks. Group 1 (control), 2 (standard), 3 and 4 animals (test) were also treated topically with vehicle, finasteride and ethanolic extract of Z. mauritiana roots and G. glabra roots respectively. Animals were observed for signs of alopecia and after treatment period one animal from each group was euthanized randomly and the skin sections from the treated area was examined for changes in follicular morphology. Statistical Analysis: Statistical analysis of data was carried out by one-way ANOVA. Using Instat version 2.1 software. Results: The Group 1, 3 and 4 animals develop alopecia and their skin section also shows bulbous and miniaturized hair follicles and prominent sebaceous gland while Group 2 (standard antiandrogenic drug finasteride treated) animals does not develop alopecia and skin samples also shows well-formed follicles and normal sebaceous gland. Conclusion: This experiments shows incapability of ethanolic extract of Z. mauritiana and G. glabra combating androgenic alopecia.

Key words: Glycyrrhiza , hair growth, Ziziphus

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.