Background: Despite a drastic increase among smokers using e-cigarette products in an attempt to wean off more harmful combustible cigarettes, there is no clear evidence promoting either the use of e-cigarettes (e-cigs) as a cessation device or understanding of the potential risks and benefits of these products, as per the U.S. Food and Drug Administration.
Case Presentation: This case has an unusual presentation of methemoglobinemia in the emergency department for the same patient twice, immediately after using e-cigs/vapes on two separate occasions.
Results: There is a possible association between e-cigarette use and methemoglobinemia. The aforementioned patient was successfully treated with the ordinary management for methemoglobinemia: methylene blue and supportive care.
Conclusion: E-cigarette use has many unrecognized and possibly fatal complications. Based on our observations, we recommend a further clinical trial to study e-cigs as a causation factor for methemoglobinemia.
Key words: E-cigarette, U.S. Food and Drug Administration (FDA), methemoglobinemia, emergency department, methylene blue, case report.
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