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Research Article

JCDR. 2021; 12(5): 1744-1753


“ANTI-THYROID ACTIVITY OF BERRY POWDER OF Hippophae rhamnoides AGAINST THYROXINE INDUCED HYPOTHYROIDISM”

K. Sowjanya*, U. Spandana, A. Meghana, Ch. Akhila, D. Sravani, K. Mercy, Pallepati Lakshmaiah.


Abstract

The present research work is to evaluate the Anti-thyroid potential of Hippophae rhamnoides [sea buckthorn] in Albino
Wister rats. Methods: Hippophae rhamnoides were used to treat infections, slows down the aging process, improves
sight and also used to treat BP (Blood Pressure) heart and liver diseases, common cold, gout, high cholesterol, ulcers
and to reduce weight. The Anti-Thyroid activity of sea buckthorn was studied by inducing hyperthyroidism in albino
Wister rats by administering Thyroxine orally for 14 days. After 14 days, collect the blood samples from the eye and
check the levels of T3, T4and TSH. From 15th day, administer the sea buckthorn berry powder and
Methimazole(standard)for 6 days (21st day) Results: In present study, it was found that thyroxin increases the levels of
T3, T4 and TSH i.e., Hyperthyroidism. By administrating Sea buckthorn berries powder, lowers the increased levels of
T3, T4 and TSH when compared to standard drug (Methimazole).

Key words: Thyroid, Sea Buckthorn, Elisa test






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