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Research Article

JCDR. 2021; 12(5): 1734-1743


Sandhya Vangara, Vaishnavi Vesta, Ratna Manjula.R, Uppuluri Spandana.


The term “Phyto” means plant while “some” means cell-like. Phytosome is a novel drug delivery technique which
contains phytoconstituents of herbal extracts. Preparation of phytosomes involve in the complexation between
phytoconstituents and phospholipids especially with phosphotidylcholine which produces lipid stable molecular
complexes. Phytosomes have water soluble inner layer and lipophilic outer layer. Phytosomes have high
pharmacokinetic and pharmacodynamic properties. They have improved bioavailability when compared to other
conventional herbal extracts. They have valuable role in pharmaceutical industustries. Phytosomes can be supplied
as natural digestive aids as they acts as antioxidants, hepatoprotective agents, anticancer agents and used as carriers
for water soluble and lipid soluble nutrients.

Key words: Drug delivery, Phytosome, Phosphotidylcholine (PC), Phospholipids complex, Bioavailability, Flavonoids, Liposomes.

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