Aims: To investigate platelet volume indices (PVI) in the spectrum of coronary artery disease and ischemic heart disease.
Methods: There were 283 instances evaluated, with 86 patients having stable coronary artery disease (stable CAD) or being admitted for a coronary artery bypass graft or coronary angiography operation. On the basis of history, specific electrocardiographic alterations, and elevated cardiac enzyme activity, 72 patients were diagnosed with unstable angina (UA) and 68 patients with acute myocardial infarction (AMI). The fourth group included 57 healthy individuals with no history of cardiac disease and an ECG that was normal.
Results: Mean platelet volume, platelet distribution width, and platelet large cell ratio- were higher in patients with AMI and UA compared with those with stable CAD and the control group.
Conclusions: Platelets are a risk factor for acquiring coronary thrombosis, which leads to myocardial infarction. Patients with higher platelet counts can be easily diagnosed during standard haematological testing and may benefit from preventive medication. Thus, PVI is a critical, and cost-effective technique that should be used and researched widely to predict the possibility of imminent acute events.
Key words: artery diseases, Ischemic heart disease, abnormal platelet function, platelet indices
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