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Drug prescribing pattern and clinical outcome in intensive care unit of a Dedicated COVID Hospital: A retrospective observational study

Teli Shaikh Emaran Shaikh Ismail, Chetan Suresh Bhangale, Harshal M Mahajan, Vijay B Gaikwad.


Abstract

Background: Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Various drug treatment protocols using drugs such as Vitamin C, hydroxychloroquine, Remdesivir, Tocilizumab, Favipiravir, Interferons, etc. were recommended by governments across globe.

Aim and Objectives: The present study aims to assess Drug Prescribing Pattern and Clinical Outcome in Intensive Care Unit (ICU) of a Dedicated COVID Hospital.

Materials and Methods: The present study was of retrospective, analytical type conducted at Government Medical College, Jalgaon which was a Dedicated COVID hospital. Medical records of 111 patients of Covid 19 who received treatment in ICU of Government Medical College, Jalgaon from August 2020 to December 2020 were included in the present study.

Results: Out of 111 patients with confirmed Covid19 infection, majority belonged to the age group of 51–60 years (24.3%), followed by 41–50 years (22.5%) and 61–70 years (20.7%). On analyzing the primary drugs prescribed, heparin was most commonly prescribed drug (95.5%) followed by corticosteroid (94.6%), Tocilizumab (39%), Oseltamivir (37%), and Remdesivir (31%). Out of patients who were cured, the majority had received heparin followed by corticosteroid, Oseltamivir, Remdesivir, Oseltamivir, and Tocilizumab.

Conclusion: In the present study corticosteroid and heparin were the most commonly prescribed drugs. Clinical outcomes were better in patient who received remdesivir, steroid, and heparin. The present study is an attempt to fill the lacuna of dearth of data on prescribing pattern of various drugs used in the treatment of moderate to severe Covid19 disease.

Key words: Prescribing; Pattern; Outcome; Coronavirus Disease






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