Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Review Article



Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective

Alfred Maroyi.

Abstract
Background: Croton membranaceus is used as herbal medicine against benign prostate hyperplasia (BPH), cough, diabetes, diarrhoea, fever, flatulence, measles, nausea and urinary retention problems. Objective: The aim of this study was to review the medicinal, phytochemical, pharmacological and toxicological properties of C. membranaceus, a potentially useful medicinal plant species in West Africa.
Methods: Literature focusing on the botany, phytochemical, pharmacological and toxicological properties of C. membranaceus were obtained from scientific databases such as SCOPUS, ScienceDirect, Pubmed, SciFinder, Medline and Google Scholar. Pre-electronic literature such as books, book chapters, journal articles, conference papers and other scientific documents were obtained from the University library.
Results: Literature search revealed that the phytochemical compounds isolated from C. membranaceus include coumarin, diterpene, glutarimide alkaloid, glutarimide peptide, labdane diterpene and phytosterol. Pharmacological studies of C. membranaceus extracts and compounds isolated from the species revealed antibacterial, antifungal, antihyperglycaemic, antioxidant, antiplasmodial, antiproliferative, cytotoxicity, hypoglycaemic and prostate growth inhibitory effects of the species.
Conclusion: The phytochemical, pharmacological and toxicological studies done so far support the uses of C. membranaceus in traditional medicine. Therefore, future research on the species should focus on detailed in vitro, in vivo and clinical studies using compounds isolated from the species as well as crude extracts.

Key words: Croton membranaceus, ethnopharmacology, Euphorbiaceae, traditional medicine, West Africa



Share this Article


Advertisement
Progress in Orthopedic Science

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.