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Case Report

Anaesth. pain intensive care. 2022; 26(1): 115-118


Systemic Thrombolysis and Anticoagulation in Postpartum Patient with Acute Respiratory Distress Syndrome (ARDS) COVID-19 and Acute Pulmonary Embolism (PE) in Intensive Care Unit: a Case Report

Samuel Hotma Rotua, Dwisetyo Gusti Arilaksono, Shinta Vera Hutajulu.




Abstract

COVID-19 has a wide range of clinical presentations from asymptomatic cases to severe respiratory distress, multi-organ dysfunction, and death. Pulmonary embolism (PE) is the most feared and severe spectrum of venous thromboembolism (VTE). We present a case of healthy 25-year-old nonsmoking pregnant woman (gravid 2, no history of abortion/miscarriage) underwent an elective caesarean section at 39 weeks of gestation after uneventful pregnancy, whom afterwards exhibit clinical presentation of pulmonary embolism (PE) overlapping with severe COVID-19 pneumonia. The diagnosis was made based on severe oxygen desaturation, McConnel sign finding on POCUS and elevated d-dimer level (34.19 mcg/mL). Alteplase and low-molecular-weight heparin were used, immediately obtained clinical improvement. We should be warned about high or extremely elevated D-Dimer measurements and severe oxygen desaturation, as possible risk markers of severe COVID-19 pneumonia in patients with high clinical suspicion of PE. Thrombolysis could be an effective and safe therapy for PE in ARDS COVID-19 patients. Furthermore, we underline that POCUS, despite its inherent limitations, could be a flexible diagnostic and management tool in refractory ARDS due to COVID-19.

Key words: COVID-19, SARS-CoV-2, Pulmonary Embolism, Thrombolytic Therapy, Postpartum Period, Point-of-Care Ultrasound






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