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JCDR. 2021; 12(3): 1899-1908


Dr. Vidya Priyadarshini, Dr. Snigdha Maity, Dr. Anupama Amruthesh.


Bisphosphonates which inhibit bone resorption are the group of drugs widely used in the management of systemic metabolic bone disease such as bone metastases, osteoporosis, Paget’s disease etc. Their ability to induce osteoblastic differentiation and inhibit recruitment of osteoclasts, bisphosphonates have provided a management strategy where it can be used alone or in conjunction with regenerative materials around bone defects both in periodontitis as well as around implants. The objective of this review article is to discuss about various groups of bisphosphonates, their actions and their potential use in the field of periodontics.

Key words: Bisphosphonates, Drugs, Periodontitis

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