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BMB. 2023; 8(1): 6-12

Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma

Serkan Kumbasar, dilruba karaca, fatma ketencı gencer, özlem khatip, hatice yaşat nacar, nazime binnur cömert, esra nazlı döktür.


Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between the patients diagnosed as low-risk or intermediate-advanced risk endometrial cancer and those with benign endometrial pathology.
Material: The study included patients underwent hysteroscopy, dilatation curettage, or endometrial biopsy with endometrial sampling due to abnormal uterine bleeding between March 2014 and April 2022.The groups were formed according to the pathology report of endometrial sampling. In addition, subgroup analysis was made based on intraoperative frozen evaluation and final pathology results .Group1 included benign endometrial pathology; Group 2 included low risk endometrial adeno cancer cases; and Group 3 were those with endometrial adeno cancer other than low risk endometrial cancer..
Results: No statistically significant difference was found between the groups in terms of neutrophil count, lymphocyte count, platelet count, eosinophil count, mpv, pdw, neutrophile to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), eosinophile to lymphocyte ratio (ELR), platelet to lymphocyte ratio (PLR) (p>0.05). Endometrial thickness, body mass index, advanced age were found to be statistically significant in the endometrial adeno cancer groups.
Conclusion: MPV, NLR, ELR, MLR, and PLR values did not show any difference between groups may be because systemic inflammation was not triggered in low-risk or medium-high-risk endometrial cancer.

Key words: MPV, NLR,ELR,MLR, PLR,Endometrium AdenoCa

Article Language: Turkish English

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