Comparison of 10% topical metronidazole versus oral metronidazole in hemorrhoidectomy in terms of post-operative pain

RMJ. 2025; 50(3): 640-643

Faiza Firdous, Sarmad Arsalan, Sehrish Siddique, Rubina Shahzad, Gohar Rasheed, Jahangir Sarwar Khan.

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Objective: To compare 10% topical metronidazole versus oral metronidazole in hemorrhoidectomy in terms of post-operative pain. Methodology: This randomized controlled trial was conducted at General Surgery department, DHQ Teaching Hospital, Rawalpindi and included a total of 60 patients. These were divided randomly into two groups. Patients in both groups underwent standard open hemorrhoidectomy. Group A was treated with oral metronidazole 400 mg thrice a day and in group-B patients, 10% metronidazole paste was applied soon after surgery and thrice daily. Visual Analogue score was recorded daily by the patient for one week The outcome was noted in both groups. All data were analyzed on SPSS 21. Results: The mean age was 45.25±11.64 years. Among group A patients the mean value of total average pain score was 6.86±0.79 whereas among group B patients, total average pain score was 5.96±0.956 (p Key words: Oral Metronidazole, topical metronidazole, hemorrhoidectomy, post-operative pain.