Background: Periodontitis and type 2 diabetes (T2D) are common public health problems affecting people worldwide, and both are involved in renal dysfunction. Serum creatinine (SCr) is an important marker for renal diseases. The recent study found that diabetes is associated with lower SCr value. In contrast, periodontitis was associated with both low and high SCr concentration and renal impairment.
Aims and Objectives: The objective of our study is to explore the interconnection and correlation among periodontitis and renal disease in T2D mellitus patients.
Materials and Methods: The study included 90 subjects aged 30–65. We assessed PD status through a standardized community periodontal index (CPI). We conducted hematological investigations to assess SCr, fasting blood glucose, postprandial blood glucose, and glycated hemoglobin. The study population was organized into four groups: Group 1 (healthy), Group 2 (PD only), Group 3 (T2D only), and Group 4 (PD and T2D). We used Pearson’s correlation, and P ˂ 0.05 was considered statistically significant.
Results: SCr was positively correlated with T2D parameters and inversely correlated with PD. A significant correlation was found with higher SCr values in Group 4 than in other study groups.
Conclusion: PD has a plausible association and synergistic effect of causing renal diseases in patients with T2D.
Key words: Periodontitis; Serum Creatinine Level; Type 2 Diabetes Mellitus
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