Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Review Article

SRP. 2020; 11(6): 598-612

Original and Innovative Advances in the Synthetic Schemes of Coumarin-Based Derivatives: A Review

Yasser Fakri Mustafa, Moath Kahtan Bashir, Mahmood Khudhayer Oglah.

Coumarin, a chemical nucleus, is award gifted from nature. This description is due to the versatile of its derivatives and the wide variety of their biological activities. Although many coumarins have been originally isolated from natural origins, there is a mounting interest in the past decades to synthesize the coumarins in the laboratory. Many synthetic routes have been documented named Perkin, Wittig, Pechmann, Claisen, Reformatsky, and Knoevenagel pathways. To maximize the yield, reduce the reaction period, minimize the side products, and make these reactions environmentally friend, several innovative approaches have been developed. These include the use of ultrasound, microwave, and solvent-free conditions to satisfy these goals. This review was focused on the traditional synthetic routes of coumarins and their innovative improvements as well as the benefits arising from the use of each of them.

Key words: Coumarins, Synthesis, Traditional methods, Innovative advances, Comparison.

Full-text options

Full-text Article

American Journal of Diagnostic Imaging


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.