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Original Article

Turk J Vasc Surg. 2020; 29(3): 189-95


The effect of deep venous thrombosis on oxidative damage and vitamin A and beta-carotene levels

Fevzi Sarper Türker, Ayşe Malbora, Mine Erişir.




Abstract

Objectives: This study aims to investigate the effect of deep venous thrombosis (DVT) on oxidative damage, vitamin A, and beta-carotene
levels.
Patients and methods: A total of 50 DVT patients (29 females, 21 males; mean age 48 years; range, 20 to 75 years) who were admitted
to the cardiovascular surgery clinic of Elazığ Training and Research Hospital with acute (0.05). In all DVT patients having thrombosis
in the distal and proximal leg veins, the mean malondialdehyde (MDA) levels significantly increased and the mean levels of vitamin A
significantly decreased, compared to healthy controls (p0.05).
Conclusion: Our study results suggest that decreased vitamin A levels may play a role in the development of DVT.

Key words: Beta-carotene, deep venous thrombosis, malondialdehyde, oxidative stress, vitamin A.






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