Background: In individuals with congestive heart failure, B-type natriuretic peptide (BNP) levels may indicate future cardiovascular complications. The majority of research has linked baseline B-type natriuretic peptide (BNP) levels to lengthy effects. The prognostic value of 1-month post-discharge BNP concentrations in acute heart failure is little understood.
Method: Patients who were hospitalized repeatedly for deteriorating heart failure were included. BNP levels were evaluated at admission, prior to discharge, and 15 days after discharge. For 6 months, patients were monitored for mortality and readmission to the hospital as endpoints.
Results: The heart failure study involved a total of 100 patients, with an average age of 60.7 ± 13.7 years. 80 patients (53%) experienced acute heart failure as a result of acute coronary syndrome, while the remaining 20 patients (45%) experienced sudden decompensation of chronic heart failure regardless of the underlying cause. The ejection fraction on average was 28.5 ± 8.8%. 13 people passed away while they were hospitalized. P value =0.002 indicates that BNP upon admission was a significant predictor of in-hospital death. Over the next one month, 5 incidents (2 fatalities and 3 re-hospitalizations) happened after release. Both the baseline and discharge BNP values (P values =0.02 and 0.002, respectively) were predictive of the 1-month outcome.
Conclusion: BNP concentration is a helpful prognostic indicator that, in confirmed cases with heart failure, predicts death and rehospitalization at 1-month follow-up and aids in the identification of patients who require more extensive medication treatment and continuous follow-up.
Key words: mortality, BNP, Heart failure, left ventricular systolic function
|
