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1800MHz Radiofrequency electromagnetic radiation: Does it affect heat shock genes expression levels in the rat brain?

Badel Arslan, Nurcan Aras, Gul Yas, Aysegul Cetinkaya.




Abstract

The brain could recognizethe cell phone radiation as environmental stress and may alter stress-related gene expression levels. Heat shock proteins (HSP) are a family of proteins that are produced by cells in response to the exposure of stressful conditions. We investigated whether exposure to 1800MHz Radiofrequency Electromagnetic Radiation (RF-EMR) recognize the expression levels of some HSPs (Cryaa, Crybb, Hsp20, Hsp25, Hsp70) in mature rat’s brain tissue. The experimental group was exposed to 1.800MHz RF-EMR in restrainer for eight weeks with 2 h/day. The specific absorption rate (SAR) was 0.06 W/kg. The sham group was kept in restrainer but not exposed to radiation. The Control group was kept under their condition. Whole brain was homogenized.ViA7 Real-Time-PCR software was used to measure CT values of the genes and ΔΔCT values were also calculated. Cryaa (p=0.02), Crybb (p=0.01), and Hsp20 (p

Key words: Electromagnetic radiation, heat-shock proteins, gene expression






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