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Anxiolytic and antidepressant-like effect of the ethanolic extract of Cassia tora seed in Swiss mice

Amit Kumar Shrivastava*, Laxmi Shrestha, Shanti Gurung, Bishal Joshi.




Abstract

Background: Cassia tora is a traditional herbal medicine has been used as an antihyperlipidemic, anti-inflammatory, anti-diabetic, expectorant, antioxidant effect, etc. Objectives: The aim of this study was to evaluate the anxiolytic and antidepressant effect of hydro-alcohol extract of Cassia tora in Swiss mice. Methods: Hydro-alcohol extract of Cassia tora was used for the evaluation of antidepressant, anxiolytic, biochemical estimation, skeletal muscle relaxant, and anoxic tolerance test. Results: The study showed that, in Locomotor activity, there was significant increase in no. of mobility count by Cassia tora extract as compared to negative control and diazepam treatment group (p

Key words: Cassia tora, antidepressant, anxiolytic, Elevated Plus Maze, Forced swim test.






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