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Review Article

SRP. 2020; 11(5): 666-671

Inhibition of Oral Bacterial Growth (Streptococcus Mutans and Porphyromonas Gingivalis) using Black Rice Bran Ethanol Extract (Oryza Sativa L.) as A Natural Mouthwash

Marhamah, Harun Achmad, Hendrastuti Handayani, Sherly Horax, Fajriani, Nurhaedah H. Galib B, Sasmita M. Arief.

Oral health problems in Indonesia are still relatively high. Indonesian National Health Research 2018 stated that oral health problemís proportion in Indonesia is 57.6%. Diseases in the oral cavity occur due to accumulation of bacteria, including bacteria that cause dental caries (Streptococcus mutans) and periodontal disease (Porphyromonas gingivalis). Current scientific methods prioritize prevention care to take care of oral health such as teeth brushing regularly using toothpaste and using mouthwash rather than surgical intervention. However, mouthwash contains alcohol, in which can increase the risk of developing oral cancer. Rice bran is a natural comestible containing antibacterial substances. Differences in pigment in rice affect its antibacterial activities. Hence, this research novelty lies in using black rice bran extract (Oryza sativa L.) formulated mouthwash. This study was a laboratory experimental study with post-test only with control group design. The study itself was divided into several phases, extract making to inhibition test. Statistical analysis resulted bran extract with concentration of 10, 20, 40, 80, and 100% with ampicillin positive control each have different inhibition zone and are statistically significant (p

Key words: Black rice bran extract, natural mouthwash Streptococcus mutans, Porphyromonas gingivalis

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