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Case Report

EJMCR. 2020; 4(12): 432-435

Detection of SARS CoV-2 RNA in pericardial effusion in a patient with cardiac tamponade - a rare case report

Elena Falchetti, Matteo Francioni, Maria Vittoria Matassini, Stefano Menzo, Laura Morbidoni, Gianfranco Maracchini, Antonio Mariani, Gian Piero Perna.

Cited by 1 Articles

Background: Coronavirus disease 2019 (COVID-19) infection can involve the cardiovascular system with many presentations, including pericardial effusion. Nevertheless, there is no evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA detected in pericardial effusion during the acute phase of COVID-19 infection.
Case Presentation: We report an acute, large but located pericardial effusion during acute COVID-19 infection, which required emergent pericardiocentesis. SARS-CoV-2 RNA was found in the pericardial fluid. The patient also presented with concomitant pleural and peritoneal effusion. The patient was treated with colchicine and was discharged 16 days later.
Conclusion: SARS-CoV-2 RNA can be detected in pericardial effusion during the acute phase of COVID-19 infection. Concomitant presence of pleural and peritoneal effusion could confirm the hypothesis of exaggerated systemic inflammatory response triggered by the virus.

Key words: COVID-19, cardiac tamponade, pericardial effusion, polyserositis

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