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Research Article

JCDR. 2021; 12(3): 535-540


A study evaluating the relationship between chromium level and myocardial infarction

Qasim H. Khalaf,Nadhum A.N.Awad ,Saad S. Hamadie.


Abstract

Background: Myocardial infarction (MI) is responsible for any condition that causes a sudden
decrease in blood flow to the heart. Certain trace elements play a role in the development of MI.
Objective: This study aimed to evaluate the association between serum chromium level and cardiac
markers in myocardial infarction.
Methodology: the current study, included 25 patients with MI and 25 healthy controls, age ranged 39-
80 years for both. Serum concentrations of essential heavy metal (Cr) were determined by flameless
atomic absorption spectrophotometry using an atomic absorption spectrophotometer, Cr was measured
at wavelength 357.9 nm using a slit width of 0.7 nm and lamp current 10 mA. To determination of
cardiac biomarker (tnhs) was measured with immunoassay kits. Serum lipids were measured using
standard commercial kits. Results; It was observed that the average concentration Cr
.292744±.1509356 vs. .677604±.1385790(μg/L), p < 0.000) were significantly higher in MI group
patients in compared with control objects. The same result was also obtained after adjustment for
cardiovascular risk factors including diabetes mellitus (DM-HBA1C and DM-FBS) and TNHS
(p < 0.05). The mean concentration of total cholesterol (TC), high-density lipoprotein cholesterol
(HDL-C), S-TG. And S-LDL were strong significantly higher in MI patients (p < 0.05). Conclusion,
the present results appeared that serum levels of essential trace element (Cr) are associated with the
presence of MI. These results add to an increasing body of evidence that, the Cr is important for
cardiovascular health.

Key words: Chromium, Troponin, Myocardial infarction, Blood samples, Atomic Absorption spectrophotometer






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