Miscarriage is a fairly relevant pathology in obstetric and gynecological practice, as it contributes not only to an increase in the number of reproductive losses, but also negatively affects the health of a woman. A study of the prevalence of this nosology will allow us to assess the need for therapeutic and preventive measures among women at risk.
Purpose: Conducting a retrospective medical and epidemiological analysis according to obstetric and gynecological hospitals in Moscow for 2014-2018 and data of the Perinatal Center of the M. P. Konchalovsky City Clinical Hospital.
Materials and methods: archival materials of gynecology hospitals in the city of Moscow have been used (including the Perinatal Center of the M. P. Konchalovsky City Clinical Hospital). The number of charts with RM cases has been 2017. For statistical analysis, in the case of comparing two dependent (paired) samples of parameters, paired Student t-test has been used. Where the compared sets of unrelated samples go against the law of normal distribution, the Mann-Whitney criterion has been used to compare them. The critical level of reliable significance of the analyzed statistical hypotheses is taken as a value of less than 0.05, since it is at this level that the probability of differences between the studied parameters is more than 95%. An analysis of the results is presented as M ± σ.
Results: The obtained data indicates a tendency toward increased occurrence of RM in Moscow (per 100 live and stillbirths) from 11.6 to 14.2 cases in 2017 and to 13.5 cases in 2018. The total reproductive loss, according to data provided by the Perinatal Center in 2018, grew up to 618.6 thousand, i.e. more than by a quarter (25.2%) The data on fertility loss due to spontaneous abortions in 2018 in Moscow is higher (412400) than across the Russian Federation (223154).
Conclusion: The retrospective medical and epidemiological analysis based on the data provided by gynecology hospitals has demonstrated a rather high proportion of RM in the structure of gynecological morbidity both in the Russian Federation and in the city of Moscow (using the data provided by the M.P. Konchalovsky Perinatal Center).
Key words: miscarriage, reproductive loss, recurrent miscarriage, infertility, abortion.