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Case Report



BENIGN SPINDEL CELL NEOPLASAM: A CENTRAL MYOFIBROMA OF MAXILLA IN MALE CHILD OF SEVEN YEARS OF AGE: A CASE REPORT

Hira Nisar,Abul Khair Zalan ,Mehreen Ismail,Sabeen Masood,Ahsan Inayat.




Abstract

Myofibroma is a rare benign spindle cell neoplasm which occurs predominantly in infants and young children. It can occur as a solitary mass or as a multicentric lesion, consisting of myofibroblasts. In oral cavity, the sites most commonly involved are the mandible, tongue, lips and buccal mucosa however, it rarely involves the maxilla. It has aggressive clinical presentation mimicking malignancies. We report a case of a male child seven years of age presented with intraoral swelling on the left palatal aspect of the maxilla that extended from primary maxillary left second molar to the distal of permanent maxillary left first molar causing the mobility of these teeth. Radiologically, the lesion was osteolytic causing marked resorption of alveolar bone and displacement of permanent maxillary left second molar. A differential diagnosis of peripheral giant cell granuloma, central giant cell granuloma, fibroma, papilloma and spindle cell neoplasm was made. After the excluding malignant and vascular involvement, the surgical excision of the lesion was planned and was carried out under general anesthesia. Histologically, benign proliferation of spindle cells was seen giving the diagnosis of benign spindle cell neoplasm. Immunoreactivity was positive for vimentin and ╬▒SMA but negative for desmin, thus confirming the diagnosis of myofibroma.

Key words: spindle cell neoplasm; myofibroma; maxilla






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