Quetiapine is an atypical antipsychotic that can be abused. Olanzapine is an another atypical antipsychotic that is similar to quetiapine in chemical structure and cases of leucopenia after olanzapine use have rarely been presented in the literature. In this report, we presented a case of high dose quetiapine abuse and olanzapine combination treatment leading to leucopenia. Blood levels returned to normal levels in a short period of time both by passing to extended release quetiapine and decreasing the daily dosage.
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