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Case Report

Primary Malignant Melanoma of Male Urethra: A Rare Occurrence

Osama Shakeel, Azfar Ali, Siddique Adnan, Wardah Jabeen, Amir Khan, Khurram Mir.

Mucosal melanoma is a subtype of Malignant Melanoma (MM). Urethral malignant melanoma is an extremely rare entity with a poor prognosis. It is associated with early recurrence and metastases.
It is a retrospective case report. Data were retrieved from the Human Information System (HIS), an electronic data-based system of Shaukat Khanum Memorial Cancer Hospital and Research Centre.
Case Discussion:
We presented a case of MM of the urethra. Forty-year-old male presented with hematuria and mass in the penile urethra for 6 months. Cystoscopy and excision of the mass were performed which showed malignant melanoma. After complete pre-operative workup and multi-disciplinary team meeting, anterior urethrectomy and suprapubic cystostomy were performed. Adjuvant interferon was given. However, the patient presented with bilateral inguinal lymph node metastases which were detected on a Positron Emission Tomography scan. He was offered radical treatment. He did not consent to the surgery. The patient died after 1 year of completion of treatment.
With little knowledge reported, the management of urethral MM is still controversial. Proper planning and the aggressive nature of treatment might help in curative management.

Key words: Malignant Melanoma, Mucosal Malignant Melanoma, Genitourinary Malignant Melanoma, Rare Urethral Cancer, Malignant Melanoma of Urethra

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The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.