Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Research Article

JCR. 2020; 7(10): 104-107


COVID-19: CURRENT KNOWLEDGE OF CLINICAL SYNDROME AND TREATMENT ADVANCES

Ragini Patil,, Dilip Gode, Pradeep Patil.

Abstract
The novel coronavirus SARS-Cov-2 infection which started as a cluster of viral pneumonia cases in Wuhan, China has rapidly spread globally though human-to-human transmission leading to a global pandemic. The causative coronavirus is structurally related to SARS coronavirus. The spike (S) protein on the virus binds to human ACE-2 receptor leading to viral entry into cell and infectivity. Most of the affected individual are either asymptomatic or experience a mild viral illness. However, a minority of patients have a complicated course with respiratory failure, ARDS and multiorgan failure leading to death, especially in those with advanced age or comorbidities. The diagnosis of COVIS-19 is by RT-PCR test on nasopharyngeal or oropharyngeal swab. Serologic tests are under development. Many antiviral medicines are currently under trial including hydroxychloroquine, remdesivir, lopinovir and ivermectin. The immune therapy options under trial include convalescent plasma, high dose intravenous immunoglobulins (IVIG) and anti-IL6 monoclonal antibody tocilizumab. Multiple trials are also underway to develop a vaccine to control this global pandemic. Various current potential targets include regions of the S protein.

Key words: SARS Cov 2, Clinical Syndrome, Pneumonia



Similar Articles

Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites