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Original Article

ECB. 2022; 11(6): 33-39


THE ROLE OF DIFFERENT CONCENTRATIONS OF COLOSTRUM SOME IMMUNOLOGICAL PARAMETERS IN MALE RATS IMMUNOSUPPRESSED

Safa masser kmosh, Ahmed J. Al-Naely.




Abstract

Present value of colostrum in this current experiment, the animals divided into one another, is a good value in this
experiment (45). The group of animals that were injected with cisplatin at a concentration (2 mg/kg) and the second treatment ((T2)
A group of animals that were injected with cisplatin at a concentration (2 mg/kg) and dosed with colium at a concentration (2
mg/kg)) A group of animals that were injected with cisplatin Concentration (2 mg/kg) the group of animals that were injected with
the drug 500) and the third treatment (T3) The group of animals that were injected with cisplatin at a concentration of (2 mg/kg)
and dosed with colostrum at a concentration of (1000) and the fourth treatment (T4) the group of animals that were injected with
cisplatin at a concentration of ( The group of animals dosed with cholesterol at a concentration of (500 mg/kg) and the sixth
treatment (T6) and the fifth treatment (T5) The group of animals that were dosed with cholesterol at a concentration (1000 mg/kg)
and the seventh factor (T7) The group of animals that were dosed with cholesterol (1500 mg/kg), after it was lowered in the
excellent study in the first treatment (T1) when compared with the control and the rest of the groups, while the number of blood
platelets witnessed a significant decrease (P> 0.05) when compared with the control, as it was noted A clear improvement in the
values The studied treatments in treatments (T2, T3, and T4) were observed, dosed with the drug and tipped with colostrum, where
the concentrations of interleukin-12, tumor necrosis factor-alpha and CIF-reactive protein were significantly (P < 0.05) compared
with the second treatment (T2) (T5, T6 and T7). An increase (< 0.05) did not reach the degree of significance compared with the
studied control and laws. The results also showed a significant decrease (P < 0.05) in the average number of white blood cells and
the percentage of neutrophils in the first treatment, while the treatments (T2, T3 and T4) Significant increase (P> 0.05) compared
with the first treatment and decreased significantly (P < 0.05) compared with the gradient, as the statistical analysis showed, a
significant increase (P> 0.05) in the percentage of lymphocytic, monocytic and eosinophilic percentage compared with Taq and its
ratio reports with the treatments The drug (T2, T3, and T4) with low concentration ratios, and from this we conclude the important
role of colostrum in reducing the damage caused by the drug.

Key words: colostrum, Cisplatin, immunity






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