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RMJ. 2021; 46(2): 270-273

Impact of influenza on hematological and serological markers

Imran Nazir, Muhammad Ajmal Farid, Rizwan Rasul Khan, Khalid Khalil, Jamal Al Ghamd, Amna Al Kalkami.

Objective: To observe the frequency and association of hematological and serological markers in influenza patients.
Methodology: This single-centered retrospective descriptive study was done in Makkah, Saudi Arabia for a 26 months period. We included all admitted confirmed H1N1 patients of both genders using simple random technique. H1N1 was confirmed by a qualitative RT-PCR test through a nasopharyngeal swab. The complete data of patients were extracted from electronic medical records. Blood complete and serological tests detail was documented. Data were analyzed by SPSS version 23. Independent samples t test was applied to see the association of independent variables with influenza A and influenza B patients.
Results: Out of 170 patients, 107(62.9%) were influenza A and 63(37.0%) were influenza B. Anemia was observed almost same (31.8% vs 31.7%) in influenza A and B (p=0.994). Leukopenia was seen 43.9% (n=47) and 25.4% (n=16) in influenza A and B patients, respectively (p=0.891). Thrombocytopenia was documented in 20.6% (n=22) influenza A while 4.8% (n=3) in influenza B (p

Key words: Influenza A and B, anemia, leukopenia, thrombocytopenia.

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