Background: In India as well as the rest of the world, cardiovascular disease (CVD) is the leading cause of death. Cardiovascular artery disease (CAD) is increasing in young adults due to epidemiological changes. Data on the epidemiological, clinical, and angiographic profiles of young individuals with ACS in India are scarce.
Methods: The current prospective observational study was conducted in the Department of Cardiology, SCB Medical College & Hospital, Cuttack, Odisha, India, with a high patient volume. A total of 30 cases (young patients 40 yrs. with acute myocardial infarction), 10 age-matched healthy controls, and 10 elderly patients (>40 yrs.) with CAD were investigated, their histories thoroughly reviewed, and their clinical conditions thoroughly examined.
Results: This study found that the average age of the cases was 34.4 years. HDL-C was lower than in the control group, and the mean blood triglyceride and LDL-cholesterol increased in the case group. Serum Lp(a) levels were significantly higher in the case group (P=0.045) compared to controls and elderly CAD.
Conclusion: The most typical ACS presentation in the young population was STE-ACS. The most prevalent risk factor was smoking. First medical contact and revascularization were delayed significantly, and most patients had a single-vessel illness.
Key words: coronary artery disease, myocardial infarction, morbidity
|